An Analysis of Gender Differences in 4645 cases of Pediatric and Adolescent Melanoma – Dermatology Times

Researchers Sabrina Dahak, MS, University associated with Arizona College of Medicine in Phoenix; Jennifer M. Fernandez, MD, RD, University of Nebraska Medical Center, Omaha; Jenna E. Koblinski, MD, Emory University School of Medication, Atlanta, Georgia; Clara Curiel-Lewandrowski, MD, College of Arizona, College of Medicine, in Tucson; and Rebecca Thiede, MD, University or college of Az College associated with Medicine, Tucson, evaluated gender differences in both presentation plus survival of pediatric and adolescent patients with melanoma.

The investigators used a retrospective cohort study, conducted using the National Cancer Database to identify biopsy-confirmed invasive primary cutaneous most cancers cases diagnosed in patients aged 0 to 21 years, between 2004 plus 2018. The study yielded 4645 instances.

The pediatric and adolescent age groups that were used are defined by the American Academy associated with Pediatrics: infant (birth to 2 years); childhood (3 to 10 years); early adolescence (11 to 14 years); middle adolescence (15 to 17 years); and late adolescence (18 in order to 21 years).

Of the 4645 pediatric melanoma cases studied, 63. 4% were females and 36. 6% were males. The particular researchers noted a significant relationship between main site on body plus gender. For example, for 34. 3% of women and 32. 9% of males, major sites included trunk; with regard to 16. 4% of females and 30. 09% associated with males, principal sites had been head and neck; 19. 5% of females plus 16% associated with males exhibited melanoma upon upper extremities, while 27. 9% of females and 16. 5% of males exhibited on the lower extremities.

Females had higher rates of superficial spreading most cancers, and males were more affected by nodular melanoma. Additionally , a lot more females were likely to be identified with stage 1 disease (67. 8%) than men (53. 6%).

The 5 and ten year overall survival rates were higher for women (95. 9% vs 93. 9% respectively) than they were regarding males (92% vs 86. 7%, respectively). The data ultimately showed that, although melanoma was less common in males than in females, males had been more likely to have a higher stage at the time of diagnosis plus OS prices, information that could be useful intended for the practitioner when creating the diagnosis and treatment plan for these populations.

Reference

Dahak S, Fernandez JM, Curiel-Lewandrowski C, Thiede R. An anaylsis of sex differences inside 4645 situations of pediatric and adolesecent melanoma. SPD 2022 47th Annual Meeting. Poster presentation, July 7 and 8. Indianapolis, Indiana.

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